Zovirax (Acyclovir)

What is this medicine?

Zovirax (Acyclovir) is used to treat herpes infections of the skin, lip, and genitals.

Viral illnesses differ from bacterial infections in that viruses are not living organisms, but rather take over living cells and reproduce themselves, often at the expense of the host cell. Acyclovir is an antiviral drug which acts against the Herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chicken pox), and the Epstein-Barr virus (mononucleosis). Acyclovir inhibits the replication of viral DNA needed to reproduce itself. Virally infected cells absorb more acyclovir than normal cells and convert more of it to an active form which prolongs its antiviral activity where it is most needed.

How should I take Zovirax?

Treatment with Zovirax topical should be started as soon as possible after the first appearance of symptoms (e.g. tingling, burning, blisters). Wash your hands before and after applying Zovirax topical. Wear a glove or a finger cot or use an applicator (e.g. cotton swab) when applying Zovirax topical to avoid spreading the virus to other body parts and to other people. Apply enough ointment to cover the lesion(s) completely. A one-half inch ribbon of ointment should cover approximately 4 square inches of surface area. Avoid getting this medication in the eyes. Zovirax topical is usually applied every 3 hours, six times a day for seven days. Follow your doctor's instructions. Use Zovirax topical for the full amount of time prescribed, even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.

What side effects may I notice from Zovirax?

No serious side effects are expected during treatment with Zovirax topical. If you suspect an allergic reaction (difficulty breathing; rash; hives; itching; swelling of your lips, tongue, or face) seek emergency medical attention. Other less serious side effects may be more likely to occur. Continue to use Zovirax topical and talk to your doctor if you experience itching, stinging, burning, or a rash. These side effects should resolve quickly. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

More Information Zovirax

Stop taking acyclovir and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects:

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
• little or no urine production; or
• unusual bleeding or bruising.

• nausea, vomiting, diarrhea, decreased appetite, or abdominal pain;
• a headache or lightheadedness; or
• joint pain.